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A combined analysis of outcome following breast cancer: differences in survival based on BRCA1/BRCA2 mutation status and administration of adjuvant treatment

BACKGROUND: The prognostic significance of germline mutations in BRCA1 and BRCA2 in women with breast cancer remains unclear. A combined analysis was performed to address this uncertainty. METHODS: Two retrospective cohorts of Ashkenazi Jewish women undergoing breast-conserving treatment for invasiv...

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Detalles Bibliográficos
Autores principales: Robson, Mark E, Chappuis, Pierre O, Satagopan, Jaya, Wong, Nora, Boyd, Jeff, Goffin, John R, Hudis, Clifford, Roberge, David, Norton, Larry, Bégin, Louis R, Offit, Kenneth, Foulkes, William D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC314444/
https://www.ncbi.nlm.nih.gov/pubmed/14680495
http://dx.doi.org/10.1186/bcr658