HIV-1 Nef Binds the DOCK2–ELMO1 Complex to Activate Rac and Inhibit Lymphocyte Chemotaxis

The infectious cycle of primate lentiviruses is intimately linked to interactions between cells of the immune system. Nef, a potent virulence factor, alters cellular environments to increase lentiviral replication in the host, yet the mechanisms underlying these effects have remained elusive. Since...

Descripción completa

Detalles Bibliográficos
Autores principales: Janardhan, Ajit, Swigut, Tomek, Hill, Brian, Myers, Michael P, Skowronski, Jacek
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC314466/
https://www.ncbi.nlm.nih.gov/pubmed/14737186
http://dx.doi.org/10.1371/journal.pbio.0020006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC314466/
https://www.ncbi.nlm.nih.gov/pubmed/14737186
http://dx.doi.org/10.1371/journal.pbio.0020006

Ejemplares similares