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Podocyte Injury Associated with Mutant α-Actinin-4

Focal segmental glomerulosclerosis (FSGS) is an important cause of proteinuria and nephrotic syndrome in humans. The pathogenesis of FSGS may be associated with glomerular visceral epithelial cell (GEC; podocyte) injury, leading to apoptosis, detachment, and “podocytopenia”, followed by glomeruloscl...

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Detalles Bibliográficos
Autores principales: Cybulsky, Andrey V., Kennedy, Chris R. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144672/
https://www.ncbi.nlm.nih.gov/pubmed/21808733
http://dx.doi.org/10.1155/2011/563128