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Current Concepts of Hyperinflammation in Chronic Granulomatous Disease

Chronic granulomatous disease (CGD) is the most common inherited disorder of phagocytic functions, caused by genetic defects in the leukocyte nicotinamide dinucleotide phosphate (NADPH) oxidase. Consequently, CGD phagocytes are impaired in destroying phagocytosed microorganisms, rendering the patien...

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Detalles Bibliográficos
Autores principales: Rieber, Nikolaus, Hector, Andreas, Kuijpers, Taco, Roos, Dirk, Hartl, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144705/
https://www.ncbi.nlm.nih.gov/pubmed/21808651
http://dx.doi.org/10.1155/2012/252460