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Genomic Regions Identified by Overlapping Clusters of Nominally-Positive SNPs from Genome-Wide Studies of Alcohol and Illegal Substance Dependence

Declaring “replication” from results of genome wide association (GWA) studies is straightforward when major gene effects provide genome-wide significance for association of the same allele of the same SNP in each of multiple independent samples. However, such unambiguous replication is unlikely when...

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Detalles Bibliográficos
Autores principales: Johnson, Catherine, Drgon, Tomas, Walther, Donna, Uhl, George R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144872/
https://www.ncbi.nlm.nih.gov/pubmed/21818250
http://dx.doi.org/10.1371/journal.pone.0019210