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Toward a Surrogate Marker of Malaria Exposure: Modeling Longitudinal Antibody Measurements under Outbreak Conditions

BACKGROUND: Biomarkers of exposure to Plasmodium falciparum would be a useful tool for the assessment of malaria burden and analysis of intervention and epidemiological studies. Antibodies to pre-erythrocytic antigens represent potential surrogates of exposure. METHODS AND FINDINGS: In an outbreak c...

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Detalles Bibliográficos
Autores principales: Campo, Joseph J., Whitman, Timothy J., Freilich, Daniel, Burgess, Timothy H., Martin, Gregory J., Doolan, Denise L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144875/
https://www.ncbi.nlm.nih.gov/pubmed/21818270
http://dx.doi.org/10.1371/journal.pone.0021826