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Targeted Ablation of Oligodendrocytes Triggers Axonal Damage

Glial dysfunction has been implicated in a number of neurodegenerative diseases. In this study we investigated the consequences of glial and oligodendrocyte ablation on neuronal integrity and survival in Drosophila and adult mice, respectively. Targeted genetic ablation of glia was achieved in the a...

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Detalles Bibliográficos
Autores principales: Ghosh, Aniket, Manrique-Hoyos, Natalia, Voigt, Aaron, Schulz, Jörg B., Kreutzfeldt, Mario, Merkler, Doron, Simons, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144945/
https://www.ncbi.nlm.nih.gov/pubmed/21818378
http://dx.doi.org/10.1371/journal.pone.0022735