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Proteomic Analysis Shows Synthetic Oleanane Triterpenoid Binds to mTOR

New multifunctional drugs that target multiple disease-relevant networks offer a novel approach to the prevention and treatment of many diseases. New synthetic oleanane triterpenoids (SO), such as CDDO (2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid) and its derivatives, are multifunctional compounds...

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Detalles Bibliográficos
Autores principales: Yore, Mark M., Kettenbach, Arminja N., Sporn, Michael B., Gerber, Scott A., Liby, Karen T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144948/
https://www.ncbi.nlm.nih.gov/pubmed/21818401
http://dx.doi.org/10.1371/journal.pone.0022862