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Proteomic Analysis Shows Synthetic Oleanane Triterpenoid Binds to mTOR
New multifunctional drugs that target multiple disease-relevant networks offer a novel approach to the prevention and treatment of many diseases. New synthetic oleanane triterpenoids (SO), such as CDDO (2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid) and its derivatives, are multifunctional compounds...
Autores principales: | Yore, Mark M., Kettenbach, Arminja N., Sporn, Michael B., Gerber, Scott A., Liby, Karen T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144948/ https://www.ncbi.nlm.nih.gov/pubmed/21818401 http://dx.doi.org/10.1371/journal.pone.0022862 |
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