Increased methylation variation in epigenetic domains across cancer types

Tumor heterogeneity is a major barrier to effective cancer diagnosis and treatment. We recently identified cancer-specific differentially DNA-methylated regions (cDMRs) in colon cancer, which also distinguish normal tissue types from each other, suggesting that these cDMRs might be generalized acros...

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Detalles Bibliográficos
Autores principales: Hansen, Kasper Daniel, Timp, Winston, Bravo, Héctor Corrada, Sabunciyan, Sarven, Langmead, Benjamin, McDonald, Oliver G., Wen, Bo, Wu, Hao, Liu, Yun, Diep, Dinh, Briem, Eirikur, Zhang, Kun, Irizarry, Rafael A., Feinberg, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145050/
https://www.ncbi.nlm.nih.gov/pubmed/21706001
http://dx.doi.org/10.1038/ng.865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145050/
https://www.ncbi.nlm.nih.gov/pubmed/21706001
http://dx.doi.org/10.1038/ng.865

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