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Contrasting human X-linked and autosomal variation in population-scale whole genome sequencing

The ratio of genetic diversity on chromosome X to that on the autosomes is sensitive to both natural selection and demography. Based on whole-genome sequences of 69 females, we report that while this ratio increases with genetic distance from genes across populations, it is lower in Europeans than i...

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Detalles Bibliográficos
Autores principales: Gottipati, Srikanth, Arbiza, Leonardo, Siepel, Adam, Clark, Andrew G., Keinan, Alon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145052/
https://www.ncbi.nlm.nih.gov/pubmed/21775991
http://dx.doi.org/10.1038/ng.877