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Metabolite-Enabled Eradication of Bacterial Persisters by Aminoglycosides

Bacterial persistence is a state in which a sub-population of dormant cells (persisters) tolerates antibiotic treatment(1-4). Bacterial persisters have been implicated in biofilms and chronic and recurrent infections(5-7). Despite this clinical relevance, there are currently no viable means for erad...

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Detalles Bibliográficos
Autores principales: Allison, Kyle R., Brynildsen, Mark P., Collins, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145328/
https://www.ncbi.nlm.nih.gov/pubmed/21562562
http://dx.doi.org/10.1038/nature10069