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Specific and Nonhomologous Isofunctional Enzymes of the Genetic Information Processing Pathways as Potential Therapeutical Targets for Tritryps

Leishmania major, Trypanosoma brucei, and Trypanosoma cruzi (Tritryps) are unicellular protozoa that cause leishmaniasis, sleeping sickness and Chagas' disease, respectively. Most drugs against them were discovered through the screening of large numbers of compounds against whole parasites. Non...

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Detalles Bibliográficos
Autores principales: Gomes, Monete Rajão, Guimarães, Ana Carolina Ramos, de Miranda, Antonio Basílio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145330/
https://www.ncbi.nlm.nih.gov/pubmed/21808726
http://dx.doi.org/10.4061/2011/543912