Histone H2B ubiquitylation and H3 lysine 4 methylation prevent ectopic silencing of euchromatic loci important for the cellular response to heat

In Saccharomyces cerevisiae, ubiquitylation of histone H2B signals methylation of histone H3 at lysine residues 4 (K4) and 79. These modifications occur at active genes but are believed to stabilize silent chromatin by limiting movement of silencing proteins away from heterochromatin domains. In the...

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Detalles Bibliográficos
Autores principales: Leung, Amy, Cajigas, Ivelisse, Jia, Peilin, Ezhkova, Elena, Brickner, Jason H., Zhao, Zhongming, Geng, Fuqiang, Tansey, William P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145549/
https://www.ncbi.nlm.nih.gov/pubmed/21680712
http://dx.doi.org/10.1091/mbc.E11-05-0426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145549/
https://www.ncbi.nlm.nih.gov/pubmed/21680712
http://dx.doi.org/10.1091/mbc.E11-05-0426

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