VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation

In endothelial cells, neuropilin-1 (NRP1) binds vascular endothelial growth factor (VEGF)-A and is thought to act as a coreceptor for kinase insert domain-containing receptor (KDR) by associating with KDR and enhancing VEGF signaling. Here we report mutations in the NRP1 b1 domain (Y297A and D320A),...

Descripción completa

Detalles Bibliográficos
Autores principales: Herzog, Birger, Pellet-Many, Caroline, Britton, Gary, Hartzoulakis, Basil, Zachary, Ian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145551/
https://www.ncbi.nlm.nih.gov/pubmed/21653826
http://dx.doi.org/10.1091/mbc.E09-12-1061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145551/
https://www.ncbi.nlm.nih.gov/pubmed/21653826
http://dx.doi.org/10.1091/mbc.E09-12-1061

Ejemplares similares