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Dynamic profiling of mRNA turnover reveals gene-specific and system-wide regulation of mRNA decay

RNA levels are determined by the rates of both transcription and decay, and a mechanistic understanding of the complex networks regulating gene expression requires methods that allow dynamic measurements of transcription and decay in living cells with minimal perturbation. Here, we describe a metabo...

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Detalles Bibliográficos
Autores principales: Munchel, Sarah E., Shultzaberger, Ryan K., Takizawa, Naoki, Weis, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145553/
https://www.ncbi.nlm.nih.gov/pubmed/21680716
http://dx.doi.org/10.1091/mbc.E11-01-0028