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Dynamic profiling of mRNA turnover reveals gene-specific and system-wide regulation of mRNA decay
RNA levels are determined by the rates of both transcription and decay, and a mechanistic understanding of the complex networks regulating gene expression requires methods that allow dynamic measurements of transcription and decay in living cells with minimal perturbation. Here, we describe a metabo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145553/ https://www.ncbi.nlm.nih.gov/pubmed/21680716 http://dx.doi.org/10.1091/mbc.E11-01-0028 |