The role of the C8 proton of ATP in the regulation of phosphoryl transfer within kinases and synthetases

BACKGROUND: The kinome comprises functionally diverse enzymes, with the current classification indicating very little about the extent of conserved regulatory mechanisms associated with phosphoryl transfer. The apparent K(m )of the kinases ranges from less than 0.4 μM to in excess of 1000 μM for ATP...

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Detalles Bibliográficos
Autores principales: Kenyon, Colin P, Steyn, Anjo, Roth, Robyn L, Steenkamp, Paul A, Nkosi, Thokozani C, Oldfield, Lyndon C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145573/
https://www.ncbi.nlm.nih.gov/pubmed/21749731
http://dx.doi.org/10.1186/1471-2091-12-36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145573/
https://www.ncbi.nlm.nih.gov/pubmed/21749731
http://dx.doi.org/10.1186/1471-2091-12-36

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