The Translation Initiation Factor eIF4E Regulates the Sex-Specific Expression of the Master Switch Gene Sxl in Drosophila melanogaster

In female fruit flies, Sex-lethal (Sxl) turns off the X chromosome dosage compensation system by a mechanism involving a combination of alternative splicing and translational repression of the male specific lethal-2 (msl-2) mRNA. A genetic screen identified the translation initiation factor eif4e as...

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Detalles Bibliográficos
Autores principales: Graham, Patricia L., Yanowitz, Judith L., Penn, Jill K. M., Deshpande, Girish, Schedl, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145617/
https://www.ncbi.nlm.nih.gov/pubmed/21829374
http://dx.doi.org/10.1371/journal.pgen.1002185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145617/
https://www.ncbi.nlm.nih.gov/pubmed/21829374
http://dx.doi.org/10.1371/journal.pgen.1002185

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