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Colon Stem Cell and Crypt Dynamics Exposed by Cell Lineage Reconstruction
Stem cell dynamics in vivo are often being studied by lineage tracing methods. Our laboratory has previously developed a retrospective method for reconstructing cell lineage trees from somatic mutations accumulated in microsatellites. This method was applied here to explore different aspects of stem...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145618/ https://www.ncbi.nlm.nih.gov/pubmed/21829376 http://dx.doi.org/10.1371/journal.pgen.1002192 |