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Colon Stem Cell and Crypt Dynamics Exposed by Cell Lineage Reconstruction

Stem cell dynamics in vivo are often being studied by lineage tracing methods. Our laboratory has previously developed a retrospective method for reconstructing cell lineage trees from somatic mutations accumulated in microsatellites. This method was applied here to explore different aspects of stem...

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Detalles Bibliográficos
Autores principales: Reizel, Yitzhak, Chapal-Ilani, Noa, Adar, Rivka, Itzkovitz, Shalev, Elbaz, Judith, Maruvka, Yosef E., Segev, Elad, Shlush, Liran I., Dekel, Nava, Shapiro, Ehud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145618/
https://www.ncbi.nlm.nih.gov/pubmed/21829376
http://dx.doi.org/10.1371/journal.pgen.1002192