Pervasive Sign Epistasis between Conjugative Plasmids and Drug-Resistance Chromosomal Mutations

Multidrug-resistant bacteria arise mostly by the accumulation of plasmids and chromosomal mutations. Typically, these resistant determinants are costly to the bacterial cell. Yet, recently, it has been found that, in Escherichia coli bacterial cells, a mutation conferring resistance to an antibiotic...

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Detalles Bibliográficos
Autores principales: Silva, Rui F., Mendonça, Sílvia C. M., Carvalho, Luís M., Reis, Ana M., Gordo, Isabel, Trindade, Sandra, Dionisio, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145620/
https://www.ncbi.nlm.nih.gov/pubmed/21829372
http://dx.doi.org/10.1371/journal.pgen.1002181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145620/
https://www.ncbi.nlm.nih.gov/pubmed/21829372
http://dx.doi.org/10.1371/journal.pgen.1002181

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