Genetic Anticipation Is Associated with Telomere Shortening in Hereditary Breast Cancer

There is increasing evidence suggesting that short telomeres and subsequent genomic instability contribute to malignant transformation. Telomere shortening has been described as a mechanism to explain genetic anticipation in dyskeratosis congenita and Li-Fraumeni syndrome. Since genetic anticipation...

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Detalles Bibliográficos
Autores principales: Martinez-Delgado, Beatriz, Yanowsky, Kira, Inglada-Perez, Lucia, Domingo, Samuel, Urioste, Miguel, Osorio, Ana, Benitez, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145621/
https://www.ncbi.nlm.nih.gov/pubmed/21829373
http://dx.doi.org/10.1371/journal.pgen.1002182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145621/
https://www.ncbi.nlm.nih.gov/pubmed/21829373
http://dx.doi.org/10.1371/journal.pgen.1002182

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