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The Shedding of CD62L (L-Selectin) Regulates the Acquisition of Lytic Activity in Human Tumor Reactive T Lymphocytes

CD62L/L-selectin is a marker found on naïve T cells and further distinguishes central memory (Tcm, CD62L+) from effector memory (Tem, CD62L−) T cells. The regulation of CD62L plays a pivotal role in controlling the traffic of T lymphocytes to and from peripheral lymph nodes. CD62L is shed from the c...

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Detalles Bibliográficos
Autores principales: Yang, Shicheng, Liu, Fang, Wang, Qiong J., Rosenberg, Steven A., Morgan, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145643/
https://www.ncbi.nlm.nih.gov/pubmed/21829468
http://dx.doi.org/10.1371/journal.pone.0022560