Cargando…

Bayesian Inference for Genomic Data Integration Reduces Misclassification Rate in Predicting Protein-Protein Interactions

Protein-protein interactions (PPIs) are essential to most fundamental cellular processes. There has been increasing interest in reconstructing PPIs networks. However, several critical difficulties exist in obtaining reliable predictions. Noticeably, false positive rates can be as high as >80%. Er...

Descripción completa

Detalles Bibliográficos
Autores principales: Xing, Chuanhua, Dunson, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145649/
https://www.ncbi.nlm.nih.gov/pubmed/21829334
http://dx.doi.org/10.1371/journal.pcbi.1002110