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The Effect of Macromolecular Crowding, Ionic Strength and Calcium Binding on Calmodulin Dynamics
The flexibility in the structure of calmodulin (CaM) allows its binding to over 300 target proteins in the cell. To investigate the structure-function relationship of CaM, we combined methods of computer simulation and experiments based on circular dichroism (CD) to investigate the structural charac...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145654/ https://www.ncbi.nlm.nih.gov/pubmed/21829336 http://dx.doi.org/10.1371/journal.pcbi.1002114 |