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X-Ray Structure Reveals a New Class and Provides Insight into Evolution of Alkaline Phosphatases

The alkaline phosphatase (AP) is a bi-metalloenzyme of potential applications in biotechnology and bioremediation, in which phosphate monoesters are nonspecifically hydrolysed under alkaline conditions to yield inorganic phosphate. The hydrolysis occurs through an enzyme intermediate in which the ca...

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Detalles Bibliográficos
Autores principales: Bihani, Subhash C., Das, Amit, Nilgiriwala, Kayzad S., Prashar, Vishal, Pirocchi, Michel, Apte, Shree Kumar, Ferrer, Jean-Luc, Hosur, Madhusoodan V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145672/
https://www.ncbi.nlm.nih.gov/pubmed/21829507
http://dx.doi.org/10.1371/journal.pone.0022767