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3′,4′-Dihydroxyflavonol Antioxidant Attenuates Diastolic Dysfunction and Cardiac Remodeling in Streptozotocin-Induced Diabetic m(Ren2)27 Rats

BACKGROUND: Diabetic cardiomyopathy (DCM) is an increasingly recognized cause of chronic heart failure amongst diabetic patients. Both increased reactive oxygen species (ROS) generation and impaired ROS scavenging have been implicated in the pathogenesis of hyperglycemia-induced left ventricular dys...

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Detalles Bibliográficos
Autores principales: Khong, Fay Lin, Zhang, Yuan, Edgley, Amanda J., Qi, Weier, Connelly, Kim A., Woodman, Owen L., Krum, Henry, Kelly, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145674/
https://www.ncbi.nlm.nih.gov/pubmed/21829510
http://dx.doi.org/10.1371/journal.pone.0022777