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A Single Amino Acid of Human Immunodeficiency Virus Type 2 Capsid Protein Affects Conformation of Two External Loops and Viral Sensitivity to TRIM5α

We previously reported that human immunodeficiency virus type 2 (HIV-2) carrying alanine or glutamine but not proline at position 120 of the capsid protein (CA) could grow in the presence of anti-viral factor TRIM5α of cynomolgus monkey (CM). To elucidate details of the interaction between the CA an...

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Detalles Bibliográficos
Autores principales: Miyamoto, Tadashi, Yokoyama, Masaru, Kono, Ken, Shioda, Tatsuo, Sato, Hironori, Nakayama, Emi E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145752/
https://www.ncbi.nlm.nih.gov/pubmed/21829511
http://dx.doi.org/10.1371/journal.pone.0022779