MicroRNA-96 Directly Inhibits γ-Globin Expression in Human Erythropoiesis

Fetal hemoglobin, HbF (α(2)γ(2)), is the main hemoglobin synthesized up to birth, but it subsequently declines and adult hemoglobin, HbA (α(2)β(2)), becomes predominant. Several studies have indicated that expression of the HbF subunit γ-globin might be regulated post-transcriptionally. This could b...

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Detalles Bibliográficos
Autores principales: Azzouzi, Imane, Moest, Hansjoerg, Winkler, Jeannine, Fauchère, Jean-Claude, Gerber, André P., Wollscheid, Bernd, Stoffel, Markus, Schmugge, Markus, Speer, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145767/
https://www.ncbi.nlm.nih.gov/pubmed/21829531
http://dx.doi.org/10.1371/journal.pone.0022838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145767/
https://www.ncbi.nlm.nih.gov/pubmed/21829531
http://dx.doi.org/10.1371/journal.pone.0022838

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