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Eos Negatively Regulates Human γ-globin Gene Transcription during Erythroid Differentiation

BACKGROUND: Human globin gene expression is precisely regulated by a complicated network of transcription factors and chromatin modifying activities during development and erythropoiesis. Eos (Ikaros family zinc finger 4, IKZF4), a member of the zinc finger transcription factor Ikaros family, plays...

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Detalles Bibliográficos
Autores principales: Yu, Hai-Chuan, Zhao, Hua-Lu, Wu, Zhi-Kui, Zhang, Jun-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145782/
https://www.ncbi.nlm.nih.gov/pubmed/21829552
http://dx.doi.org/10.1371/journal.pone.0022907