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Epigenetic Instability due to Defective Replication of Structured DNA

The accurate propagation of histone marks during chromosomal replication is proposed to rely on the tight coupling of replication with the recycling of parental histones to the daughter strands. Here, we show in the avian cell line DT40 that REV1, a key regulator of DNA translesion synthesis at the...

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Detalles Bibliográficos
Autores principales: Sarkies, Peter, Reams, Charlie, Simpson, Laura J., Sale, Julian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145961/
https://www.ncbi.nlm.nih.gov/pubmed/21145480
http://dx.doi.org/10.1016/j.molcel.2010.11.009