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Epigenetic Instability due to Defective Replication of Structured DNA
The accurate propagation of histone marks during chromosomal replication is proposed to rely on the tight coupling of replication with the recycling of parental histones to the daughter strands. Here, we show in the avian cell line DT40 that REV1, a key regulator of DNA translesion synthesis at the...
Autores principales: | Sarkies, Peter, Reams, Charlie, Simpson, Laura J., Sale, Julian E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145961/ https://www.ncbi.nlm.nih.gov/pubmed/21145480 http://dx.doi.org/10.1016/j.molcel.2010.11.009 |
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