Thermostabilisation of an Agonist-Bound Conformation of the Human Adenosine A(2A) Receptor

The adenosine A(2A) receptor (A(2A)R) is a G-protein-coupled receptor that plays a key role in transmembrane signalling mediated by the agonist adenosine. The structure of A(2A)R was determined recently in an antagonist-bound conformation, which was facilitated by the T4 lysozyme fusion in cytoplasm...

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Detalles Bibliográficos
Autores principales: Lebon, Guillaume, Bennett, Kirstie, Jazayeri, Ali, Tate, Christopher G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145977/
https://www.ncbi.nlm.nih.gov/pubmed/21501622
http://dx.doi.org/10.1016/j.jmb.2011.03.075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145977/
https://www.ncbi.nlm.nih.gov/pubmed/21501622
http://dx.doi.org/10.1016/j.jmb.2011.03.075

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