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A Novel Elevated Plus-Maze Procedure to Avoid the One-Trial Tolerance Problem

The elevated plus-maze (EPM) test is one of the most commonly used behavioral assays to evaluate anxiety-related behavior in rodents. It is an economic test (5 min duration) without prior conditioning of the animals. The critical measure for anxiety is the time spent in the open arms of the maze. A...

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Detalles Bibliográficos
Autores principales: Schneider, Peggy, Ho, Ying-Jui, Spanagel, Rainer, Pawlak, Cornelius Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146044/
https://www.ncbi.nlm.nih.gov/pubmed/21845176
http://dx.doi.org/10.3389/fnbeh.2011.00043