Dynamic CpG island methylation landscape in oocytes and preimplantation embryos

Elucidating how and to what extent CpG islands (CGIs) are methylated in germ cells is essential to understand genomic imprinting and epigenetic reprogramming1-3. Here, we present the first integrated epigenomic analysis of mammalian oocytes, identifying over a thousand CGIs methylated in mature oocy...

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Detalles Bibliográficos
Autores principales: Smallwood, Sébastien A., Tomizawa, Shin-ichi, Krueger, Felix, Ruf, Nico, Carli, Natasha, Segonds-Pichon, Anne, Sato, Shun, Hata, Kenichiro, Andrews, Simon R., Kelsey, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146050/
https://www.ncbi.nlm.nih.gov/pubmed/21706000
http://dx.doi.org/10.1038/ng.864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146050/
https://www.ncbi.nlm.nih.gov/pubmed/21706000
http://dx.doi.org/10.1038/ng.864

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