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Development and validation of a headspace gas chromatographic method for the determination of residual solvents in arterolane (RBx11160) maleate bulk drug

OBJECTIVE: Arterolane maleate is an antimalarial drug currently under Phase III clinical evaluation, and presents a simple, economical and scalable synthesis, and does not suffer from safety problems. Arterolane maleate is more active than artemisinin; and is cheap to produce. It has a longer lifeti...

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Detalles Bibliográficos
Autores principales: Gupta, Abhishek, Singh, Yogendra, Srinivas, Kona S., Jain, Garima, Sreekumar, V. B., Semwal, Vinod Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications Pvt Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146089/
https://www.ncbi.nlm.nih.gov/pubmed/21814428
http://dx.doi.org/10.4103/0975-7406.62706