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Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase

In vivo studies suggest that replication forks are arrested due to encounters with head-on transcription complexes. Yet, the fate of the replisome and RNA polymerase (RNAP) following a head-on collision is unknown. Here, we find that the E. coli replisome stalls upon collision with a head-on transcr...

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Detalles Bibliográficos
Autores principales: Pomerantz, Richard T., O'Donnell, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146238/
https://www.ncbi.nlm.nih.gov/pubmed/20436399
http://dx.doi.org/10.3791/1919