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Direct Restart of a Replication Fork Stalled by a Head-On RNA Polymerase
In vivo studies suggest that replication forks are arrested due to encounters with head-on transcription complexes. Yet, the fate of the replisome and RNA polymerase (RNAP) following a head-on collision is unknown. Here, we find that the E. coli replisome stalls upon collision with a head-on transcr...
Autores principales: | Pomerantz, Richard T., O'Donnell, Mike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MyJove Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146238/ https://www.ncbi.nlm.nih.gov/pubmed/20436399 http://dx.doi.org/10.3791/1919 |
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