Cross-Talk between the Catalytic Core and the Regulatory Domain in Cystathionine β-Synthase: Study by Differential Covalent Labeling and Computational Modeling

[Image: see text] Cystathionine β-synthase (CBS) is a modular enzyme which catalyzes condensation of serine with homocysteine. Cross-talk between the catalytic core and the C-terminal regulatory domain modulates the enzyme activity. The regulatory domain imposes an autoinhibition action that is alle...

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Detalles Bibliográficos
Autores principales: Hnízda, Aleš, Spiwok, Vojtěch, Jurga, Vojtěch, Kožich, Viktor, Kodíček, Milan, Kraus, Jan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146298/
https://www.ncbi.nlm.nih.gov/pubmed/21062078
http://dx.doi.org/10.1021/bi101384m

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146298/
https://www.ncbi.nlm.nih.gov/pubmed/21062078
http://dx.doi.org/10.1021/bi101384m

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