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The MEK-ERK pathway negatively regulates bim expression through the 3' UTR in sympathetic neurons
BACKGROUND: Apoptosis plays a critical role during neuronal development and disease. Developing sympathetic neurons depend on nerve growth factor (NGF) for survival during the late embryonic and early postnatal period and die by apoptosis in its absence. The proapoptotic BH3-only protein Bim increas...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146425/ https://www.ncbi.nlm.nih.gov/pubmed/21762482 http://dx.doi.org/10.1186/1471-2202-12-69 |