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ER stress drives Lipocalin 2 upregulation in prostate cancer cells in an NF-κB-dependent manner

BACKGROUND: Tumor cells adapt to endoplasmic reticulum (ER) stress through a set of conserved intracellular pathways, as part of a process termed the unfolded protein response (UPR). The expression of UPR genes/proteins correlates with increasing progression and poor clinical outcome of several tumo...

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Detalles Bibliográficos
Autores principales: Mahadevan, Navin R, Rodvold, Jeffrey, Almanza, Gonzalo, Pérez, Antonio Fernández, Wheeler, Matthew C, Zanetti, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146445/
https://www.ncbi.nlm.nih.gov/pubmed/21649922
http://dx.doi.org/10.1186/1471-2407-11-229