Mechanism of PhosphoThreonine/Serine Recognition and Specificity for Modular Domains from All-atom Molecular Dynamics

BACKGROUND: Phosphopeptide-binding domains mediate many vital cellular processes such as signal transduction and protein recognition. We studied three well-known domains important for signal transduction: BRCT repeats, WW domain and forkhead-associated (FHA) domain. The first two recognize both phos...

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Detalles Bibliográficos
Autores principales: Huang, Yu-ming M, Chang, Chia-en A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146460/
https://www.ncbi.nlm.nih.gov/pubmed/21612598
http://dx.doi.org/10.1186/2046-1682-4-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146460/
https://www.ncbi.nlm.nih.gov/pubmed/21612598
http://dx.doi.org/10.1186/2046-1682-4-12

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