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The UBC9 E2 SUMO Conjugating Enzyme Binds the PR-Set7 Histone Methyltransferase to Facilitate Target Gene Repression

PR-Set7/Set8/KMT5a is a chromatin-modifying enzyme that specifically monomethylates lysine 20 of histone H4 (H4K20me1). In this study we attempted to identify PR-Set7-interacting proteins reasoning that these proteins would provide important insights into the role of PR-Set7 in transcriptional regul...

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Detalles Bibliográficos
Autores principales: Spektor, Tanya M., Congdon, Lauren M., Veerappan, Chendhore S., Rice, Judd C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146489/
https://www.ncbi.nlm.nih.gov/pubmed/21829513
http://dx.doi.org/10.1371/journal.pone.0022785