A Heart-Hand Syndrome Gene: Tfap2b Plays a Critical Role in the Development and Remodeling of Mouse Ductus Arteriosus and Limb Patterning

BACKGROUND: Patent ductus arteriosus (PDA) is one of the most common forms of congenital heart disease. Mutations in transcription factor TFAP2B cause Char syndrome, a human disorder characterized by PDA, facial dysmorphysm and hand anomalies. Animal research data are needed to understand the mechan...

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Detalles Bibliográficos
Autores principales: Zhao, Feng, Bosserhoff, Anja-Katrin, Buettner, Reinhard, Moser, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146506/
https://www.ncbi.nlm.nih.gov/pubmed/21829553
http://dx.doi.org/10.1371/journal.pone.0022908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146506/
https://www.ncbi.nlm.nih.gov/pubmed/21829553
http://dx.doi.org/10.1371/journal.pone.0022908

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