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Genome-Wide Gene Expression Analysis Suggests an Important Role of Hypoxia in the Pathogenesis of Endemic Osteochondropathy Kashin-Beck Disease

Kashin-Beck Disease (KBD) is an endemic osteochondropathy, the pathogenesis of which remains unclear now. In this study, we compared gene expression profiles of articular cartilage derived respectively from KBD patients and normal controls. Total RNA were isolated, amplified, labeled and hybridized...

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Detalles Bibliográficos
Autores principales: Zhang, Feng, Guo, Xiong, Wang, Weizhuo, Yan, Hua, Li, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146522/
https://www.ncbi.nlm.nih.gov/pubmed/21829570
http://dx.doi.org/10.1371/journal.pone.0022983