Multiple ATR-Chk1 Pathway Proteins Preferentially Associate with Checkpoint-Inducing DNA Substrates

The ATR-Chk1 DNA damage checkpoint pathway is a critical regulator of the cellular response to DNA damage and replication stress in human cells. The variety of environmental, chemotherapeutic, and carcinogenic agents that activate this signal transduction pathway do so primarily through the formatio...

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Detalles Bibliográficos
Autores principales: Yilmaz, Seçil, Sancar, Aziz, Kemp, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146532/
https://www.ncbi.nlm.nih.gov/pubmed/21829571
http://dx.doi.org/10.1371/journal.pone.0022986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146532/
https://www.ncbi.nlm.nih.gov/pubmed/21829571
http://dx.doi.org/10.1371/journal.pone.0022986

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