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Highly Anomalous Energetics of Protein Cold Denaturation Linked to Folding-Unfolding Kinetics

Despite several careful experimental analyses, it is not yet clear whether protein cold-denaturation is just a “mirror image” of heat denaturation or whether it shows unique structural and energetic features. Here we report that, for a well-characterized small protein, heat denaturation and cold den...

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Detalles Bibliográficos
Autores principales: Romero-Romero, M. Luisa, Inglés-Prieto, Alvaro, Ibarra-Molero, Beatriz, Sanchez-Ruiz, Jose M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146537/
https://www.ncbi.nlm.nih.gov/pubmed/21829584
http://dx.doi.org/10.1371/journal.pone.0023050