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Quantitative Analysis of Protein Phosphorylations and Interactions by Multi-Colour IP-FCM as an Input for Kinetic Modelling of Signalling Networks

BACKGROUND: To understand complex biological signalling mechanisms, mathematical modelling of signal transduction pathways has been applied successfully in last few years. However, precise quantitative measurements of signal transduction events such as activation-dependent phosphorylation of protein...

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Detalles Bibliográficos
Autores principales: Deswal, Sumit, Schulze, Anna K., Höfer, Thomas, Schamel, Wolfgang W. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146539/
https://www.ncbi.nlm.nih.gov/pubmed/21829558
http://dx.doi.org/10.1371/journal.pone.0022928