Modeling Disordered Regions in Proteins Using Rosetta

Protein structure prediction methods such as Rosetta search for the lowest energy conformation of the polypeptide chain. However, the experimentally observed native state is at a minimum of the free energy, rather than the energy. The neglect of the missing configurational entropy contribution to th...

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Detalles Bibliográficos
Autores principales: Wang, Ray Yu-Ruei, Han, Yan, Krassovsky, Kristina, Sheffler, William, Tyka, Michael, Baker, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146542/
https://www.ncbi.nlm.nih.gov/pubmed/21829444
http://dx.doi.org/10.1371/journal.pone.0022060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146542/
https://www.ncbi.nlm.nih.gov/pubmed/21829444
http://dx.doi.org/10.1371/journal.pone.0022060

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