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Absence of α-synuclein affects dopamine metabolism and synaptic markers in the striatum of aging mice()

Despite numerous evidences for neurotoxicity of overexpressed α-synuclein, a protective function was suggested for endogenous α-synuclein and other members of the synuclein family. This protective role is most important for and evident in presynaptic terminals, where synucleins are normally accumula...

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Detalles Bibliográficos
Autores principales: Al-Wandi, Abdelmojib, Ninkina, Natalia, Millership, Steven, Williamson, Sally J.M., Jones, Paul A., Buchman, Vladimir L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146702/
https://www.ncbi.nlm.nih.gov/pubmed/19097673
http://dx.doi.org/10.1016/j.neurobiolaging.2008.11.001